Cutting Edge: Antigen-Independent CD8 T Cell

Proliferation Cutting Edge: Antigen-Independent CD8 T Cell

CCD107a Expression and IFN-γ Production as Markers for Evaluation of Cytotoxic CD3+ CD8+ T Cell Response to CMV Antigen in Women with Recurrent Spontaneous Abortion

Cutting Edge: B Cells Promote CD8 T Cell Activation in MRL-Fas Mice Independently of MHC Class I Antigen Presentation

Cells after Influenza A Virus Infection Cutting Edge: Antigen Presentation to CD8 T

Cutting edge: B cells promote CD8+ T cell activation in MRL-Fas(lpr) mice independently of MHC class I antigen presentation.

Spontaneous CD8+ T cell activation in MRL-Faslpr mice is B cell dependent. It is unclear whether this B-dependent activation is mediated by direct Ag presentation via MHC class I proteins (i.e., cross-presentation) or whether activation occurs by an indirect mechanism, e.g., via effects on CD4+ cells. To determine how CD8+ T cell activation is promoted by B cells, we created mixed bone marrow c...